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Academic approach

MS sherpa

MS sherpa is part of several study programs, collaborating with several clinics and academic partners.

Study overview

DOT MS Study

Goal

Can we safely discontinue first-line medication in MS patients with long-term absence of inflammation, without the return of inflammatory disease activity clinically and radiologically?
Is it possible to detect and predict (return of) inflammatory disease activity and disease progression with digital biomarkers using mobile applications such as MS sherpa?

Study group

(Amsterdam UMC) N= 130 patients

Planning

Protocol approved by METC, started: Jun20
recruitment ongoing

APPS MS study

Goal

Develop and explore measuring methods using built-in sensors of conventional smartphones and wearables to quantify fatigue, disease activity and progression in a day-to-day setting in patients with MS.

Study group

N= >250, >125 intervention group, 125 control group, collaboration with Amsterdam UMC and 3 STZ hospitals

Planning

inclusion completed 31 dec 2019, study completion
planned 31 dec 2020

MS Self study

Goal

Develop and explore measuring methods using built-in sensors of conventional smartphones and wearables to quantify fatigue, disease activity and progression in a day-to-day setting in patients with MS.

Study group

N= 25 MS patients, N= 79 Healthy controls

Planning

completed

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Goal

Develop and explore measuring methods using built-in sensors of conventional smartphones and wearables to quantify fatigue, disease activity and progression in a day-to-day setting in patients with MS.

Study group

N= >250, >125 intervention group, 125 control group, collaboration with Amsterdam UMC and 3 STZ hospitals

Planning

inclusion completed 31 dec 2019, study completion
planned 31 dec 2020